明升体育

张梅，博士，明升体育，博/硕士生导师，明升体育药学院中药化学系教师，四川省精品课程《中药制剂分析》负责人。现任世界中医药学会联合会道地药材专委会常务理事，中华中医药学会中药分析分会常务委员，四川省分析测试学会色谱学委员会副主任委员。一直从事中药物质基础及中药质量控制与评价等方面的教学及科研工作，作为课题负责人及主研人员承担了国家自然科学基金及部省局级科研项目近40项，获得授权发明专利5项，作为主持人及第二主研获得四川省和成都市科技进步三等奖共3项。围绕以上研究工作在Analytical Chemistry、Natural Product Reports、Phytomedicine、Sensors and Actuators B: Chemical、Food Chemistry （中科院1区）、Journal of Ethnopharmacology、Microchemical Journal、Phytochemistry（中科院2区）等相关杂志及学术会议上公开发表及交流论文170余篇。作为主编、副主编及编委参与编写《当代药用植物典》系列专著及国家“十四·五”、“十三·五”、“十二·五”、“十一·五”、“十·五”等规划教材及教参20余部。

研究领域涉及（1）中药物质基础及作用机制研究；（2）中药质量控制及评价方法研究；（3）中药分析新方法及新技术研究；（4）中药体内药物及其代谢产物分析等。

联系方式：zhangmei63@cdutcm.edu.cn

代表性成果

（一）承担项目

1. 国家自然科学基金面上项目：基于“体内谱效关联-网络靶点重构”研究补肾活血方防治早期糖尿病视网膜水肿效应物质基础及作用机制（82174273），2022/01- 2025/12，55万，负责人

2. 国家自然科学基金面上项目，基于“活性成分群-细胞效应表达” 研究补肾活血方配伍多点调控HIF-1/VEGF信号途径防治DR作用机制（81774202），2018/01-2021/12，55万，负责人

3. 四川省应用基础研究重点项目：基于多维谱效关系及体内动态效应研究补肾活血方防治DR药效物质基础（2017JY0013） 2017/01-2019/12，30万，负责人

4. 明升体育一流学科项目：中药有效有害成分快速分析方法研究（CXTD2018010），2018/01-2022/12，100万，负责人

（二）发表论文

1. Ting Wang, Jinchao Wei, Zehua Cheng, Mai Luo, Liang Zou, Lele Zhang, Mei Zhang^*, Peng Li^*. Plasmonic Nanocubes with a Controllable “Crescent Arc” Facet: Tunable Hotspot Engineering for Highly Reliable and Sensitive SERS Detection. Analytical Chemistry. .2024, 96, 17453-17462 https://doi.org/10.1021/acs.analchem.4c05334.

2. Maohua Yang, Liangli Li, Chunni Zhao, Mei Zhang^* , Mingyan Jia^*. A colorimetric sensor array for the rapid identification of benzylisoquinoline alkaloids and Coptidis Rhizoma based on urease inhibition.. Food Chemistry, 470 (2025) 142610. https://doi.org/10.1016/j.foodchem.2024.142610

3. Yuan Ren, Huan Liang, Mengjun Xie^*, Mei Zhang^*. Natural plant medications for the treatment of retinal diseases: The blood-retinal barrier as a clue. Phytomedicine 130 (2024) 155568. https://doi.org/10.1016/j.phymed.2024.155568.

4. Liangli Li , Maohua Yang , Mei Zhang^*, Mingyan Jia^*. Machine learning-assisted colorimetric sensor array for rapid identification of adulterated Panax notoginseng powder. LWT - Food Science and Technology 207 (2024) 116680. https://doi.org/10.1016/j.lwt.2024.116680.

5. Huan Liang, Yuan Ren, Yuxia Huang, Xuejun Xie, ^*, Mei Zhang^*. Treatment of diabetic retinopathy with herbs for tonifying kidney and activating blood circulation: A review of pharmacological studies. Journal of Ethnopharmacology. 328 (2024) 118078. https://doi.org/10.1016/j.jep.2024.118078

6. Dan Cai, Yun-Yun Liu, Xin-Ping Tang, Mei Zhang^*, Yong-Xian Cheng^*. Minor ergosteroids and a 19-nor labdane-type diterpenoid with anti-inflammatory effects from Ganoderma lucidum. Phytochemistry 222 (2024) 114052. https://doi.org/10.1016/j.phytochem.2024.114052.

7. Jing Li , Xin Guo, Yuxia Huang, Yuan Ren, Huan Liang, Xuejun Xie^*, Mei Zhang^*.Exploring the mechanism of Bushen Huoxue prescription in the treatment of early diabetic retinal edema from the perspective of inner blood-retinal barrier injury. Journal of Ethnopharmacology. 323 (2024) 117658 https://doi.org/10.1016/j.jep.2023.117658

8. Mingyan Jia^*, Wenxing Mi 1, Xiaowei Guo, Mei Zhang^*. A ratiometric fluorescent sensor based on dual-emitting carbon dots for the rapid detection of sulfite. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 325 (2025) 125132. https://doi.org/10.1016/j.saa.2024.125132.

9. Kejun Li , Qingze Liu , Yan Lian , Yanping Wang , Yuemei Chen , Xin Yuan^* , Mei Zhang^*. Enzymatic reaction modulated hydride generation of arsenic for parathion-methyl monitoring in traditional Chinese medicine by atomic fluorescence spectrometry. Microchemical Journal 191 (2023) 108882 https://doi.org/10.1016/j.microc.2023.108882

10. Maohua Yang, Mei Zhang, Mingyan Jia^*. Optical sensor arrays for the detection and discrimination of natural products. Natural Product Reports. DOI: 10.1039/d2np00065b.

（三）招生专业